CAPS (gene)

Calcyphosine

Identifiers

CAPS; CAPS1; MGC126562

External IDs

OMIM: 114212 HomoloGene: 37871 GeneCards: CAPS Gene

Gene Ontology
Molecular function	• calcium ion binding
Cellular component	• intracellular • cytoplasm
Biological process	• intracellular signal transduction
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

n/a

n/a

n/a

RefSeq (mRNA)

NM_004058.3

n/a

RefSeq (protein)

NP_004049.1

n/a

Location (UCSC)

Chr 19:
5.91 – 5.92 Mb

n/a

PubMed search

[1]

n/a

Calcyphosin is a protein that in humans is encoded by the CAPS gene.^[1]^[2]^[3]

This gene encodes a calcium-binding protein, which may play a role in the regulation of ion transport. A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit. Alternative splicing of this gene generates two transcript variants.^[3]

References

^ El Housni H, Radulescu A, Lecocq R, Dumont JE, Christophe D (Aug 1997). "Cloning and sequence analysis of human calcyphosine complementary DNA". Biochim Biophys Acta 1352 (3): 249–52. PMID 9224948.
^ Lefort A, Passage E, Libert F, Szpirer J, Vassart G, Mattei MG (Feb 1991). "Localization of human calcyphosine gene (CAPS) to the p13.3 region of chromosome 19 by in situ hybridization". Cytogenet Cell Genet 54 (3-4): 154–5. doi:10.1159/000132981. PMID 2265558.
^ ^a ^b "Entrez Gene: CAPS calcyphosine". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=828.

Lefort A, Lecocq R, Libert F, et al. (1989). "Cloning and sequencing of a calcium-binding protein regulated by cyclic AMP in the thyroid.". EMBO J. 8 (1): 111–6. PMC 400778. PMID 2540953. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=400778.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Clément S, Dumont JE, Schurmans S (1997). "Loss of calcyphosine gene expression in mouse and other rodents.". Biochem. Biophys. Res. Commun. 232 (2): 407–13. doi:10.1006/bbrc.1997.6297. PMID 9125191.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.

CAPS (gene)

References

Further reading